产品货号：
JN2065
中文名称：
重组SARS-CoV-2 Papain-like Protease
英文名称：
Recombinant SARS-CoV-2 Papain-like Protease
产品规格：
10μg|50μg
发货周期：
1～3天
产品价格：
询价
本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 Papain-like Protease（Glu1564-Lys187）。
Accession #:QHD43415.1
蛋白别称：Papain-like Protease;PLpro;PL-PRO;pp1a;Replicase polyprotein 1a
贮存液：20mM Tris-HCl,10mM Mercaptoethanol [BME],20% Glycerol,pH7.5，0.2μm过滤
质量控制：
分子量：35.8kDa
实测分子量：34kDa（还原条件下）
纯度：＞90%（还原SDS-PAGE）
保存条件：-20℃，可稳定保存6个月，应避免反复冻融。
背景资料：
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases,a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro).These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV.PLpro is a cysteine protease located within the non-structural protein 3 (NS3) section of the viral polypeptide.PLPro activity is required to process the viral polyprotein into functional,mature subunits;specifically,PLPro cleaves a site at the amino-terminus of the viral replicase region.In addition to its role in viral protein maturation,PLPro possesses a deubiquitinating and deISGylating activity.In vivo,this protease antagonizes innate immunity by inhibiting IRF3-induced production of type I interferons.
相关搜索：重组SARS-CoV-2 Papain-like Protease，重组SARS-CoV-2木瓜蛋白酶样蛋白酶，重组新型冠状病毒Papain-like Protease，重组2019-nCoV Papain-like Protease，重组新冠病毒PLpro，重组新型冠状病毒PL-PRO，Recombinant SARS-CoV-2 Papain-like Protease
Accession #:QHD43415.1
蛋白别称：Papain-like Protease;PLpro;PL-PRO;pp1a;Replicase polyprotein 1a
贮存液：20mM Tris-HCl,10mM Mercaptoethanol [BME],20% Glycerol,pH7.5，0.2μm过滤
质量控制：
分子量：35.8kDa
实测分子量：34kDa（还原条件下）
纯度：＞90%（还原SDS-PAGE）
保存条件：-20℃，可稳定保存6个月，应避免反复冻融。
背景资料：
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases,a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro).These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV.PLpro is a cysteine protease located within the non-structural protein 3 (NS3) section of the viral polypeptide.PLPro activity is required to process the viral polyprotein into functional,mature subunits;specifically,PLPro cleaves a site at the amino-terminus of the viral replicase region.In addition to its role in viral protein maturation,PLPro possesses a deubiquitinating and deISGylating activity.In vivo,this protease antagonizes innate immunity by inhibiting IRF3-induced production of type I interferons.
相关搜索：重组SARS-CoV-2 Papain-like Protease，重组SARS-CoV-2木瓜蛋白酶样蛋白酶，重组新型冠状病毒Papain-like Protease，重组2019-nCoV Papain-like Protease，重组新冠病毒PLpro，重组新型冠状病毒PL-PRO，Recombinant SARS-CoV-2 Papain-like Protease